a tool for identifying drug-targetable redox-active disulphides

Metallothionein-1

Intramolecular

Cysteine 13 and cysteine 26

A redox-regulated disulphide may form within Metallothionein-1 between cysteines 13 and 26.

Details

Redox score ?

90

PDB code

Structure name

solution structure of the beta-domain of mouse metallothionein-1

Structure deposition date

1999-11-20

Thiol separation (Å)

4

Half-sphere exposure sum ?

nan

Minimum pK_a ?

9

% buried

0

Peptide accession

Residue number A

13

Residue number B

26

Peptide name

Metallothionein-1

Ligandability

Cysteine 13 of Metallothionein-1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 26 of Metallothionein-1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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